Auditory brainstem pathways do not develop properly without microglia

Auditory pathways in the brainstem do not fully mature without microglia clearing away extra cell connections. This crucial function occurs even when pruning by microglia is delayed, according to new research published in eNeuro. Sensitive hearing requires precise connections between neurons in the auditory brainstem. Early in development, support cells called microglia prune away unnecessary […]

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Beyond secretion of insulin, the novel function of beta cells in regulating glucose homeostasis

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang’s group and Antonio Vidal-Puig’s group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29a, miR-29b and miR-29c) in response to high levels of free fatty acids (FFAs). These β cell-derived miR-29s are delivered to the liver, promoting insulin […]

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